The immunohistochemistry (IHC) analyses of tumor tissues for expression levels of And‐1 and cleaved caspase‐3 antibodies demonstrated that CH3‐inhibited And‐1 expression and induced the expression of cleaved caspase‐3, which indicated the apoptosis in treated ovarian and breast tumors (Figure 6C, F). This evidence concerns the gene WDHD1 and breast neoplasm.