As mentioned above, Gao et al. reported that triptonide diminishes TNBC tumor growth via inhibiting expression of several stemness genes, but promoting Snail1 overexpression and induces a Snail-associated feedback mechanism of triptonide-resistance in a single in vitro-produced triptonide-resistant HCC1806 cell line [39]; however, whether triptonide affects Snail1 expression in TNBC cell lines without in vitro artificial induction of triptonide-resistance has not been addressed in the paper [39]. Here, SNAI1 is linked to neoplasm.