Current guidelines of the American Heart Association and the European Society of Cardiology highlighted the lack of useful biomarkers to predict in-hospital complications and short/long term prognosis of patients with MI, recommending for this purpose only to measure troponin and brain natriuretic peptide (BNP) serum levels, with the latter associated with a low level of evidence [6, 7]. The gene discussed is NPPB; the disease is myocardial infarction.