We analyzed the relationship between mRNA expression and OS in this network, and we found that high expression of CCND1 and VEGFA is an indicator of poor prognosis for colon cancer (Fig. 9B) and that the expression of CCND1 and VEGFA is associated with macrophage infiltration (Fig. 9C). The gene discussed is CCND1; the disease is malignant colon neoplasm.