Finally, IHC analysis was performed to detect the Ki67 and E-cadherin expression, which revealed that CXCL13 promoted the tumor Ki67 expression and reduced E-cadherin expression, while A3149 inhibited CXCL13’s promotion of tumor Ki67 expression and the inhibition of E-cadherin expression (Fig. 7D, E). Here, CXCL13 is linked to neoplasm.