CD44 and liver cancer: Indeed, TM4SF5 has been previously reported to be related to liver cancer progression, together with cell markers CD133+, CD44+(bound to TM4SF5)/CD24−/ALDH+/Bmi+, and protein tyrosine phosphatase receptor type F (PTPRF−) [34, 41], in addition to laminin γ2+, AFP+, MCP-1+, CD34+, and FUCA+ (AFU) shown in this study.