TM4SF5 and hepatocellular carcinoma: Furthermore, public GEO data (GSE14520) analysis showed that TM4SF5 expression was highly elevated in HCC patients (p < 0.0001), and among samples those showing increased TM4SF5 expression in HCC, SLAMF7 (p < 0.0001), MICA (p = 0.0161), ULBP1 (p < 0.0001), and ULBP2 (p = 0.0926) were oppositely decreased (Fig. 6E).