CD8A and neoplasm: Further clustering analysis for T cell and myeloid compartments based on defined markers (see Methods) led to the identification of four CD4+ and two CD8+ T cell subsets, eight monocyte/macrophage subsets, and six dendritic cell (DC) subsets in most of the patients from both tumor and nonmalignant tissues (Fig. 5A–B, Supplementary Fig. 9).