FlowSOM clustering of 182,800 T cells from wildtype (n = 5) and Osm−/− tumours (n = 5) identified 20 populations including CD8pos (progenitor, cytotoxic, exhausted and memory), CD4pos (naïve, Th1, Th2, memory and Treg) and γδ T cells (Supplementary Fig. 6f, g). Here, OSM is linked to neoplasm.