Specifically, the MØ subset (M/N/B_C10), which express markers consistent with an immunosuppressive tumour-associated MØ (TAM) phenotype (CD11bpos; F4/80pos; MHCIIhigh)9, was significantly decreased in Osm−/− tumours (Supplementary Fig. 6a and e). The gene discussed is OSM; the disease is neoplasm.