LIFR and hepatocellular carcinoma: Three days and 17 days after hydrodynamic transfection, we performed tail injection of control adenovirus or LIFR-expressing adenovirus, finding that adenoviral delivery of LIFR increased LIFR protein levels in liver tissues (Supplementary Fig. 2d) and prolonged survival in mice with oncogene-induced HCC (Supplementary Fig. 2e).