As indicated by western blot analysis, expression of LOX-1, c-MYC, and SULT2B1 in tumor tissues of nude mice was lowered by knocking down OLR1, whilst SULT2B1 expression in tumor tissues of nude mice was markedly strengthened by oe-SULT2B1 treatment in the presence of sh-OLR1As (Fig. 7A). This evidence concerns the gene OLR1 and neoplasm.