As reflected by RT-qPCR and immunohistochemical staining in 120 cases of colon cancer tissues and adjacent normal tissues, OLR1 expression was potently higher in colon cancer tissues than that in adjacent normal tissues, and LOX-1 protein was mainly located in the cell membrane of colon cancer tissues (Fig. 1G, H). This evidence concerns the gene OLR1 and malignant colon neoplasm.