CASP3 and age-related macular degeneration: It also decreasesthe expression of caspase-3, thus preventing glaucoma and AMD.210,216 AXT has a protective effect on the retina and treats injuries causedby the elevated intraocular pressure217 and hence inhibits the glaucomatous retinal degeneration.209 Nowadays, drug macromolecules as angiogenesisinhibitors including aflibercept, pegaptanib, and ranibizumab withmolecular weights of 97, 50, and 48 kDa, respectively, are AMD’sfirst treatment.