PTOV1 and hepatocellular carcinoma: Although PTOV1 increased cell apoptosis, inhibited cell migration and invasion.[4] Overexpression of PTOV1 suggests poor prognosis in hepatocellular carcinoma(HCC),[5] and nasopharyngeal carcinoma (NPC),[6] cervical cancer,[7] epithelial ovarian cancer.[8] High expression of PTOV1was significantly associated with advanced TNM stage.[9]