In the TCGA dataset, it can be found that XRCC1 has the highest mutation rate in Uterine Corpus Endometrial Carcinoma samples, Cervical squamous cell carcinoma and endocervical adenocarcinoma has a relatively high mutation rate, and ovarian cancer has a low mutation rate, indicating that the mutation of this gene may lead to endometrial cancer and cervical cancer. The gene discussed is XRCC1; the disease is endocervical adenocarcinoma.