APC and neoplasm: The original tumor tissue of SNU‐4146 had a TP53 mutation (c.817C > T/p.R273C) with VAF of 1, which appeared in a relatively early stage of the tumor evolution, and two APC mutations (c.637C > T/p.R213* and c.1312+2T > G/p.X438_splice) with VAFs of 0.51 and 0.43, respectively (Figure S5B, Supporting Information).