HINT1 and neurodegenerative disease: The proteins (SNCA, HSPA8, HINT1) are associated with neurodegenerative diseases like Parkinson’s, Alzheimer’s, Huntington's, Prion disorders, and Fronto-temporal dementia (Lin et al., 2020, Matsumura et al., 2013, Shchagina et al., 2020, Sung et al., 2005, Wyttenbach and Arrigo, 2009).