Compared with the NC group, type 2 diabetic mice were presented with reduced Caveolin-1 (green) and GLUT4 (red) fluorescence intensity (fluorescence intensity of Caveolin-1: 11.46 ± 3.29 vs. 6.74 ± 1.35, GLUT4: 9.915 ± 1.29 vs. 5.87 ± 0.98). This evidence concerns the gene CAV1 and type 2 diabetes mellitus.