There were 15 genes with the highest interaction links identified as the endometriosis-associated hub genes, including ESR1, TP53, FN1, EGFR, STAT3, VIM, CDKN1A, CDKN2A, CCND1, NFKB1, AKT1, UCHL1, BCL2, PTEN, and PGR (Figure 3). This evidence concerns the gene CDKN2A and endometriosis.