Our results are in accordance with these findings and suggest that the KCNQ1OT1/miR-338-3p/ITGA5 and KCNQ1OT1/miR-29c-3p/KDELC1 axes have important roles in determining the prognosis of HNSCC patients. Here, POGLUT2 is linked to head and neck squamous cell carcinoma.