Furthermore, the levels of four candidates were remarkably different between the T2DM + CRC and T2DM groups, namely, B2MG (FC = 1.257, p = 0.031), LV218 (FC = 2.067, p = 0.015), MDN1 (FC = 2.274, p = 0.032) and PZP (FC = 3.032, p = 0.027), and PZP exhibited the largest discrimination level (Table 2). The gene discussed is MDN1; the disease is type 2 diabetes mellitus.