Examples of miRNA regulators of TGF-β signaling include miR-423-5p, miR-552, and miR-17–92 cluster (miR-17, miR-18a, miR-19a, miR-19b, miR-20a and miR-92a) in prostate cancer, colorectal cancer, and pancreatic cancer (Cioffi et al., 2015; Zhao et al., 2019; Shan et al., 2020). This evidence concerns the gene TGFB1 and familial pancreatic carcinoma.