SMURF2 and non-small cell lung carcinoma: miR-128-3p, which was markedly up-regulated in cisplatin-resistant NSCLC cell lines, induced mesenchymal and stem-like properties by inhibiting two negative regulators of the TGF-β pathway, SMAD-specific E3 ubiquitin protein ligase 2 (SMURF2) and protein phosphatase 1c (PP1c), which resulted in the activation of TGF-β pathway, eventually leading to EMT and the development of cisplatin resistance (Cai et al., 2017).