Besides cancer, SRSF6 has been associated with numerous human diseases, such as pleural fibrosis (Liang et al., 2021), Huntington’s disease (Cabrera and Lucas, 2017), Alzheimer’s disease (Mai et al., 2019), diabetes (Juan-Mateu et al., 2018), and systemic sclerosis (Manetti et al., 2011). This evidence concerns the gene SRSF6 and systemic sclerosis.