In medullary thyroid carcinoma (MTC), a somatic missense substitution mutation in the exon 11 of oncogene RET gene significantly increased the interaction between SRSF6 protein and exon 11 of RET RNA, and in turn increased the transcripts with the inclusion of exon 11 and the expression of full RET protein (Pecce et al., 2018), which may promote cell proliferation and tumorigenesis. This evidence concerns the gene SRSF6 and medullary thyroid gland carcinoma.