FMR1 intronic transcript 1 (FMR1-IT1) is also known as FMR1 intronic transcript 1 (non-protein coding) or Fragile X Mental Retardation Syndrome Protein (FMRP) or FMR1, there were evidence that FMRP regulated tumor invasiveness-related pathways in melanoma cells by impacting cell migration, invasion and adhesion (Zalfa et al., 2017), and its overexpression was associated with lung metastasis of murine breast cancer (Lucá et al., 2013). This evidence concerns the gene FMR1-IT1 and melanoma.