ELN and myocardial infarction: Researchers examined the images of elastin and mature elastin fibers using an elastin/tropoelastin-specific contrast agent (i.e., Gd-ESMA) by constructing myocardial ischemia model in mice, and found the presence of tropoelastin and mature elastin in the infarct scar regions, and this presence was associated with improved ejection fraction of heart after MI in vivo (Protti et al., 2015).