So far, several large-scale concurrent hearing and genetic newborn screening programs have reported that using the limited genetic screening panel including even a small number of variants in genes commonly associated with hearing loss (GJB2, GJB3, SLC26A4, and MT-RNR1) could improve the effectiveness of elucidating etiologies, informing high-risk newborns and their maternal relatives of hearing loss (26, 27). This evidence concerns the gene GJB3 and hearing loss disorder.