Although SNHG1 has been reported to function as an oncogene through sponging miR-195-5p (15), miR-377-3p (16), and miR-195 (17) in HCC, in the present study, we made use of The Cancer Genome Atlas (TCGA) database and identified a novel molecular mechanism of SNHG1 in HCC growth. Here, SNHG1 is linked to hepatocellular carcinoma.