In TCGA cohort, the enrichment score of the high-risk group was higher relative to the low-risk group in 73.91% (17/23) of cancer therapeutic prediction signature sets, including “Basal_differentiation”, “Cell_cycle”, “DNA_replication”, “EGFR_ligands”, “EMT_differentiation”, “Hypoxia”, “Immune_differentiation”, “Mismatch_repair”, “Nucleotide_excision_repair”, “Oocyte_meiosis”, “p53_signaling_casacde”, “Progesterone-mediated_oocyte_maturation”, “Proteasome”, “Spliceosome”, “Pyrimidine_metabolism”, “Systemic_lupus_erythematosus”, and “Viral_carcinogenesis” (Figure 7E; p < 0.05). Here, EGFR is linked to cancer.