HSF2 and shigellosis: Moreover, KEGG enrichment analysis showed that HSF2 was related to the cell cycle, ubiquitin-mediated proteolysis, the Fanconi anemia pathway, basal transcription factors, the spliceosome, etc. In addition, herpes simplex virus 1 infection, hepatitis B, shigellosis, Salmonella infection, and human T-cell leukemia virus 1 infection, which are related to the immune response, were also correlated with HSF2 in the KEGG pathways (Figure 7B).