Therefore, preoperative routine examination of CD4+ T lymphocytes in patients with HIV-related RCC is an aspect of evaluating whether patients can tolerate surgery, but CD4+ T lymphocytes do not serve as a good predictor of the survival prognosis of these patients; therefore, it is necessary to find prognostic predictors for patients with HIV-related RCC. This evidence concerns the gene CD4 and renal cell carcinoma.