The overall mean IGF-1 concentrations in IUGR-S and IUGR-I were 43% and 35% lower, respectively, compared to the CON-S (IUGR-S, 68.47 ± 13.16 ng/mL; IUGR-I, 79.02 ± 10.55 ng/mL; CON-S, 121.05 ± 14.22 ng/mL). The gene discussed is IGF1; the disease is fetal growth restriction.