Alternately, pharmacological inhibition or genetic deletion of FAAH, pharmacological inhibition of MAGL or activation of CB1 improves chemically induced colitis in rodents (Massa et al., 2004; Alhouayek et al., 2011; Fichna et al., 2014; Sałaga et al., 2014; Sasso et al., 2015; Shamran et al., 2017). Here, FAAH is linked to colitis.