Impairment of ADAR-mediated RNA editing activity has been associated with different neurological disorders, including ALS (Aizawa et al., 2010; Hideyama et al., 2012), epilepsy (Srivastava et al., 2017), Alzheimer's disease (Khermesh et al., 2016), autoimmune disorders (Rice et al., 2012), and ASD (Eran et al., 2013; Tran et al., 2019). The gene discussed is ADAR; the disease is autoimmune disease.