The authors thank Baoliang Song (Wuhan University, Wuhan, China) and Boliang Li (Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China) for providing Soat1fl/fl mice, Hongliang Li (Wuhan University, Wuhan, China) for Tlr4–/– mice, and Jinxiang Zhang (Wuhan Union Hospital, Wuhan, China) for CRC patient samples. Here, TLR4 is linked to colorectal carcinoma.