In addition, ACE2 has assumed a prominentrole in the fight against the COVID-19 pandemic-causing virus SARS-CoV-2,as it is the very first receptor in the host of the viral spike protein.The binding of the spike protein to ACE2 triggers a cascade of eventsthat eventually leads the virus to enter the host cell and initiateits life cycle. Here, ACE2 is linked to COVID-19.