Interestingly, our analysis of the GEO database entry GSE29221 revealed that DNA methyltransferase (DNMT1) expression was significantly decreased in the skeletal muscles of individuals with type 2 diabetes (n = 11) as compared with those without type 2 diabetes (n = 13) (153.1 ± 19.2 vs 283.9 ± 181.2; p = 0.013). Here, DNMT1 is linked to type 2 diabetes mellitus.