Potential applications of home vision monitoring include early detection of progression from intermediate to neovascular AMD (nAMD), fellow-eye conversion in patients with nAMD in the first eye, as well as monitoring patients receiving anti–vascular endothelial growth factor (VEGF) treatment for nAMD, diabetic macular edema or macular edema secondary to retinal vein occlusions. The gene discussed is VEGFA; the disease is macular retinal edema.