EGFR and lung carcinoma: Lastly, by observing tumor cell lysis of the lung cancer lines H292 (EGFR WT) and H1975 (EGFR L858R/T790M) treated with amivantamab in the presence of human peripheral blood mononuclear cells (PBMCs) in vitro, amivantamab was demonstrated to induce ADCC in a similar fashion to cetuximab [77].