ARMCX3 and type 2 diabetes mellitus: In addition, ARMCX3 is related to the regulation of cholesterol, fatty acids, glucose metabolism, and muscle development or hypertrophy because ARMCX3 methylation causes the downregulation of HDAC7 and FYN, which lead to a low birth weight (LBW), insulin resistance, and T2D (Broholm et al., 2020).