Those highlighted the intensive and integrated kidney disease care, including low protein diet, control of blood pressure, sugar, hyperlipidemia, correction of metabolic acidosis by sodium bicarbonate, and adequate administration of erythropoietin stimulating agents might slow the renal progression that is independently associated with lower risk for heart failure, myocardial infarction, and peripheral arterial disease (33, 34). This evidence concerns the gene EPO and hyperlipidemia.