Gliomas with lower ANXA1 expression are more likely to belong to proneural (PN) and neural (NE) subtypes and have a good prognosis, while gliomas with high ANXA1 expression are more likely to belong to mesenchymal (MES) and classical (CL) subtypes and have poor survival (all p < 2.00e-16). The gene discussed is ANXA1; the disease is glioma.