The ANXA1 expression was highest in IDH wild-type and lowest in IDH mutation and 1p/19q co-deletion in LGGs (all p ≤ 5e-5, Figure 1C left), while ANXA1 expression was higher in the IDH wild-type than in IDH mutant gliomas in GBMs (p < 5e-11, Figure 1C right). Here, ANXA1 is linked to central nervous system cancer.