DNMT1 and neoplasm: In vitro and in vivo studies carried out by Li et al. revealed that miR-148b could function as a tumor suppressor, the downregulation of this miRNA induced EMT, migration, invasion, and increased MMP-9 activity in endometrial cancer cell lines, as well as metastasis in a nude mouse model, additionally, DNA methyltransferase 1 (DNMT1) was determined as the target gene of miR-148b (Li et al., 2019).