RNASE1 and familial pancreatic carcinoma: Interestingly, we observed that there are reports of mutations and copy number variation in PAIP2B, PRDX1, RNASE1, BARD1, UHMK1, and RPL3L genes associated with pancreatic cancer (Bartsch et al., 2005; Barton, 2016; Tang et al., 2017; Wang et al., 2017; Alimirzaie et al., 2018; Grant et al., 2018).