FMF patients with attack had a higher frequency of a median (IQR) ESR (mm/h) and CRP (mg/L) levels than attack-free patients [22 (24) vs. 9 (13), p < 0.001 and 40.5 (71) vs. 3 (8), p < 0.001, respectively]. Here, ESR1 is linked to familial Mediterranean fever.