In addition, several molecular markers, including isocitrate dehydrogenase 1 (IDH1), epidermal growth factor receptor (EGFR), O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation, telomerase reverse transcriptase (TERT), 1p/19q codeletion, phosphatase and tensin homolog (PTEN), and α-thalassemia/mental-retardation-syndrome-X-linked gene (ATRX), have been shown to be glioma prognostic factors (4–7), and their threshold values have been validated clinically. This evidence concerns the gene EGFR and central nervous system cancer.