By induction of colitis, as shown in Figure 3, the TNBS group had significantly (P ≤ 0.00001) higher mean serum levels of inflammatory cytokines, TNF-α (44 vs.75 pg./ml), IL-6 (21 vs.41 pg./ml), and NO (6 vs. 24 μm/ml), compared to healthy control rats. The gene discussed is TNF; the disease is colitis.