However higher PCT levels have been reported in patients with gram-negative infection than those with gram positive and fungal infection.12 We did not find significant difference in PCT levels in gram positive and gram-negative bacteremia probably because of small number of patients with positive blood culture results, secondly in Japan study PCT concentrations were significantly higher in patients who were infected with E.coli,13 whereas in our study population no patient was infected with E. Coli, thirdly we did not perform fungal culture. Here, CALCA is linked to fungal infectious disease.