TNRC6B and adenocarcinoma: Of note, SNVs shared between the DMBA-induced organoid-derived adenocarcinomas and 0.6 μM DMBA-treated organoids (prior to injection into the subcutis of nude mice) were limited to 10 genes, including Tnrc6b and Vps13d, which were selected by the IGV (Figure 1B).