Nevertheless,in comparison with the other causes of ARDS (median IL-6 level is 10- to 200-fold higher than COVID-19) the lower levels of circulating cytokines in COVID-19 may not be representative of lung inflammation and need to be determined whether COVID-19 related ARDS phenotype is associated with the cytokine storm (73, 75). This evidence concerns the gene IL6 and acute respiratory distress syndrome.