RGS10 and hypersensitivity pneumonitis: More importantly, at 5 dpi, Rgs10-/- mice developed severe lung damage demonstrated by massive inflammatory cell infiltration, such as neutrophils, into the bronchioles (bronchiolitis) (Figures 2A, B) and inflammatory cells aggregation into the alveolar walls and spaces (alveolitis) (Figures 2A, C).