FCGR3A and infection: These findings suggest that the fate of a monocyte hinges upon its basal activation state, and that the infection potential differs both within an individuals’ monocyte population, in part based on the differentiation status of the cell (i.e. CD16-positivity), but also between individuals, where a CD16- cell from one individual may have a higher antiviral state than a CD16+ cell from another individual.