In a global cancer context, aberrant CPEB expression has been linked to cell proliferation, invasion, malignant transformation and angiogenesis through translational reprogramming in numerous types of cancer (D’Ambrogio et al., 2013), indicating that mRNA processing is important for tumor growth; however, not all CPEBs play the same role in tumorigenesis. The gene discussed is CPEB1; the disease is cancer.